Degos-Like Lesions Associated with Systemic Lupus Erythematosus.
- Author:
Min Soo JANG
1
;
Jong Bin PARK
;
Myeong Hyeon YANG
;
Ji Yun JANG
;
Joon Hee KIM
;
Kang Hoon LEE
;
Geun Tae KIM
;
Hyun HWANGBO
;
Kee Suck SUH
Author Information
- Publication Type:Case Report
- Keywords: Degos disease; Degos-like lesions; Systemic lupus erythematosus
- MeSH: Adult; Autoimmune Diseases; Central Nervous System; Diagnosis; Erythema; Female; Fingers; Follow-Up Studies; Humans; Infarction; Knee; Lupus Erythematosus, Systemic*; Malignant Atrophic Papulosis; Skin; Vasculitis; Vasculitis, Central Nervous System
- From:Annals of Dermatology 2017;29(2):215-218
- CountryRepublic of Korea
- Language:English
- Abstract: Degos disease, also referred to as malignant atrophic papulosis, was first described in 1941 by Köhlmeier and was independently described by Degos in 1942. Degos disease is characterized by diffuse, papular skin eruptions with porcelain-white centers and slightly raised erythematous telangiectatic rims associated with bowel infarction. Although the etiology of Degos disease is unknown, autoimmune diseases, coagulation disorders, and vasculitis have all been considered as underlying pathogenic mechanisms. Approximately 15% of Degos disease have a benign course limited to the skin and no history of gastrointestinal or central nervous system (CNS) involvement. A 29-year-old female with history of systemic lupus erythematosus (SLE) presented with a 2-year history of asymptomatic lesions on the dorsum of all fingers and both knees. The patient had only skin lesions and no gastrointestinal or CNS vasculitis symptoms. Her skin lesions were umbilicated, atrophic porcelain-white lesions with a rim of erythema. On the basis of clinical, histologic, and laboratory findings, a diagnosis of Degos-like lesions associated with SLE was made. The patient had been treated for SLE for 7 years. Her treatment regimen was maintained over a 2 month follow-up period, and the skin lesions improved slightly with no development of new lesions.
