Rho signaling inhibitor, Y-27632, inhibits invasiveness of metastastic hepatocellular carcinoma in a mouse model.
- Author:
Feng XUE
1
;
Jian-jun ZHANG
;
Feng QIU
;
Ming ZHANG
;
Xiao-song CHEN
;
Qi-gen LI
;
Long-zhi HAN
;
Zhi-feng XI
;
Qiang XIA
Author Information
1. Organ Transplantation Center, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200127, China.
- Publication Type:Journal Article
- MeSH:
Actins;
chemistry;
Amides;
therapeutic use;
Animals;
Apoptosis;
drug effects;
Cytoskeleton;
drug effects;
Enzyme Inhibitors;
therapeutic use;
Female;
Liver Neoplasms, Experimental;
drug therapy;
pathology;
Mice;
Neoplasm Invasiveness;
Neoplasm Metastasis;
Pyridines;
therapeutic use;
ras Proteins;
analysis;
rho-Associated Kinases;
analysis;
antagonists & inhibitors;
rhoA GTP-Binding Protein;
analysis;
rhoC GTP-Binding Protein
- From:
Chinese Medical Journal
2007;120(24):2304-2307
- CountryChina
- Language:English
