Surgical management and preservation of laryngeal function for senile patients with advanced laryngeal carcinoma.
- Author:
Dao-gong ZHANG
1
;
Han-bing ZHANG
;
Xin-yong LUAN
;
Xin-liang PAN
;
Guang XIE
Author Information
- Publication Type:Journal Article
- MeSH: Aged; Aged, 80 and over; Carcinoma, Squamous Cell; pathology; radiotherapy; surgery; Female; Follow-Up Studies; Humans; Kaplan-Meier Estimate; Laryngeal Neoplasms; pathology; radiotherapy; surgery; Laryngectomy; methods; Larynx; pathology; surgery; Lymphatic Metastasis; Male; Neck Dissection; methods; Neoplasm Recurrence, Local; Neoplasm Staging; Postoperative Period; Radiotherapy, Adjuvant; Retrospective Studies
- From: Chinese Journal of Oncology 2007;29(5):379-381
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo explore the methods of surgical treatment and preservation of laryngeal function in senile patients with advanced laryngeal carcinoma.
METHODSA retrospective data review of 87 advanced laryngeal carcinoma patients aged over 65 years was carried out. Of these 87 patients treated by different modes of surgery, 48 had supraglottic cancer, 35 glottic cancer and 4 subglottic cancer. The surgery modes consisted of major partial laryngectomy in 36 patients, subtotal partial laryngectomy with laryngoplasty in 21 and total laryngectomy in 30. All patients received postoperative radiotherapy to a dose of 50-60 Gy. Kaplan-Meier method was used to analyze the survival.
RESULTSThe overall 3- and 5-year survival rate was 73.2% and 67.4%, respectively. The ultimate rate of larynx preservation was 65.5%. Of 57 patients with partial laryngectomy, 46 were decannulated with a decannulation rate of 80.7%. Yet, in all patients, the nasal feeding tube was removed and food intake per os was resumed. All patients who underwent partial laryngectomy regained their phonation function.
CONCLUSIONIt is safe and effective to treat and preserve laryngeal function surgically in the senile patients with advanced laryngeal carcinoma. The key points to achieve this are selection of proper patient, renovation of surgical procedure and improvement of surgical skill.
