Analysis of auditory steady-state response to multiple simultaneous stimuli and cochlea morphology in guinea pigs with posterior semicircular canal fistula.
- Author:
Nan-ping XIE
1
;
Guo-qiang CHEN
;
Xing YANG
;
Si-yun SHU
Author Information
- Publication Type:Journal Article
- MeSH: Animals; Audiometry, Pure-Tone; methods; Auditory Threshold; physiology; Cochlea; pathology; Evoked Potentials, Auditory; Fistula; pathology; physiopathology; Guinea Pigs; Labyrinth Diseases; pathology; physiopathology; Semicircular Canals
- From: Journal of Southern Medical University 2006;26(4):495-497
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo observe the changes of auditory steady-state response (ASSR) threshold in guinea pigs with posterior semicircular canal fistula.
METHODSIn 10 guinea pigs, a window was opened in the posterior semicircular canal of the left ear with the right ear serving as the control for testing the ASSR under anesthesia with pentobarbital sodium.
RESULTSThe mean and standard deviation of ASSR threshold (dB SPL) at 0.5, 1, 2, and 4 kHz in the left ear was 35.00+/-14.33, 25.50+/-12.37, 20.00+/-9.37 and 20.00+/-9.18, respectively, and was 31.00+/-16.19, 25.50+/-12.34, 18.00+/-6.96 and 18.50+/-6.71 in the right ear, respectively. Paired-sample t test showed no significant difference in the ASSR at the same frequency between the two ears.
CONCLUSIONSmall fistula by surgery causes no significant hearing loss in guinea pigs.
