A rare case of Silver-Russell syndrome in adult and literature review.

Author: Pei-ying LU ^{1
,

2} ; Wei GU ¹ ; Xiao-hong PANG ¹ ; Peng-fei SHAN ¹ ;
Author Information

1. Department of Endocrinology, the Second Affiliate Hospital, Zhejiang University School of Medicine, Hangzhou 310009, China
2. 2. Department of Internal Medicine, The Branch of Zhejiang Hospital, Hangzhou 310030, China.
Publication Type:Case Reports
MeSH: Female; Humans; Silver-Russell Syndrome; Young Adult
From: Journal of Zhejiang University. Medical sciences 2015;44(3):335-338
CountryChina
Language:Chinese
Abstract: Silver-Russell syndrome (SRS) is a rare genetic disorder with non-specific manifestations and severity, so that the clinical diagnosis of SRS remains difficult. We reported a 23-year-old female patient with SRS characterized with short body stature, asymmetry, obesity, fifth finger clinodactyly and dislocation of hip. The patient had a past history of lengthening operation on the right lower limb at the age of 10. Chromosome analysis revealed (46, XX). The patient was admitted due to severe asymmetry in low extremities caused by right-side obesity. After successful orthopedic surgery in the right hips and thighs the symptoms of patient were relieved.