Research advances on prenatal maternal serum markers for screening adverse pregnancy outcomes.
- Author:
Qin-qin SHEN
1
,
2
;
Tan ZHANG
1
;
Author Information
1. The Medical College of Ningbo University, Ningbo 315211, China
2. 2. Ningbo Women and Children's Hospital, Ningbo 315012, China.
- Publication Type:Journal Article
- MeSH:
Biomarkers;
blood;
Chromosomes, Human, Pair 18;
Down Syndrome;
Female;
Humans;
Neural Tube Defects;
Pregnancy;
Pregnancy Outcome;
Prenatal Diagnosis;
Trisomy
- From:
Journal of Zhejiang University. Medical sciences
2015;44(3):339-343
- CountryChina
- Language:Chinese
-
Abstract:
The routine prenatal maternal serum testing is widely used for screening of birth defects, including Down syndrome, trisomy 18 syndrome and neural tube defects. The testing results are also associated with other adverse pregnant outcomes such as fetal surface structural abnormalities, gestational hypertension disease, intrahepatic cholestasis of pregnancy, premature rupture of membranes, abortion, stillbirth, intrauterine growth restriction and macrosomia; therefore the abnormal levels of serum markers might be used for predicting these adverse pregnant outcomes.
