The value of narrow-band imaging with magnifying endoscopy in diagnosis of early gastric cancer: a meta-analysis.
- Author:
Wei HUANG
1
;
Lei WANG
1
;
Jing DU
1
;
Jian-min YANG
1
Author Information
- Publication Type:Journal Article
- MeSH: Early Detection of Cancer; Gastroscopy; methods; Humans; Narrow Band Imaging; Sensitivity and Specificity; Stomach Neoplasms; diagnosis
- From: Journal of Zhejiang University. Medical sciences 2015;44(4):435-442
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo assess the diagnostic value of narrow-band imaging with magnifying endoscopy (NBI-ME) for early gastric cancer (EGC).
METHODSWe searched PubMed, Embase, Web of Science and the Cochrane Library for literature of NBI-ME in diagnosis of EGC, and then performed meta-analysis.
RESULTSA total of 12 articles involving 2 278 samples from 2 048 patients were included. The overall sensitivity of NBI-ME for diagnosis of EGC was 0.84 [95% CI: 0.80~0.87], specificity was 0.96 (95% CI: 0.95~0.97),and area under the symmetric receiver operator characteristic curve (AUC) was 0.9592. The AUC value of the NBI-ME plus conventional white light endoscopy (C-WLE) subgroup (0.9706) was higher than that of NBI-ME alone (0.8162). The incremental yield of NBI-ME plus C-WLE over C-WLE was significant (IY = 9.4%, P = 0.011), while NBI-ME alone over C-WLE was not significant (IY = 0.8%, P = 0.498).
CONCLUSIONSThe results show that NBI-ME plus C-WLE is an effective and preferable method for diagnosis of EGC; however, NBI-ME alone is not superior to C-WLE.
