Highlights of the third edition of Chinese guidelines for AIDS diagnosis and treatment(2015).
- Author:
Jian-Jun SUN
1
;
Hong-Zhou LU
2
Author Information
1. Department of Infectious Diseases, Shanghai Public Health Clinical Center, Fudan University, Shanghai 201508, China.
2. Department of Infectious Diseases, Huashan Hospital, Fudan University, Shanghai 200040, China.
- Publication Type:Journal Article
- MeSH:
Acquired Immunodeficiency Syndrome;
diagnosis;
drug therapy;
CD4 Lymphocyte Count;
Child;
China;
Female;
HIV Infections;
diagnosis;
drug therapy;
Humans;
Practice Guidelines as Topic;
Pregnancy
- From:
Journal of Zhejiang University. Medical sciences
2015;44(6):597-602
- CountryChina
- Language:Chinese
-
Abstract:
The third edition of Chinese guidelines for AIDS diagnosis and treatment was launched in 2015 by AIDS Professional Group, Society of Infectious Diseases, Chinese Medical Association. New edition emphasizes the importance of timely initiation of anti-retroviral therapy(ART). Like other guidelines, this edition recommends that once the HIV infection is confirmed, the ART should be initiated timely. For patients with HIV and opportunistic infections, once the infections are under control, the ART should be initiated without delay. For AIDS patients complicated with tuberculosis whose CD4 cell counts are less than 200/μL, the ART should start within 2 weeks after the initiation of anti-tuberculosis treatment. In this guideline, the drugs with severe toxicities and poor tolerance are excluded, and new drugs are added such as rilpivrine (RPV) and atazanavir (ATV) because of less toxicity and higher HIV depression effect; and 3TC+TDF+EFV is recommended as the first line regimen. As for children with HIV infection, especially for those less than 5 years, once the infection is confirmed the ART should be initiated immediately. For the prevention of HIV mother to children transmission, new edition recommends that HIV-infected pregnant women start ART early and keep on ART all their lives.
