The effect of platelet-rich plasma on the distraction osteogenesis.
- Author:
Quan-feng LUO
1
;
Xing WANG
;
Xiao-xia WANG
;
Biao YIN
;
Zi-li LI
;
Cheng LIANG
Author Information
- Publication Type:Journal Article
- MeSH: Animals; Blood Platelets; physiology; Cells, Cultured; Immunohistochemistry; Male; Osteoblasts; cytology; metabolism; Osteogenesis; physiology; Osteogenesis, Distraction; Platelet Count; Rabbits
- From: Chinese Journal of Plastic Surgery 2004;20(5):376-379
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo observe the effect of the platelet-rich plasma (PRP) on osteogenesis during bone distraction.
METHODSThe osteoblasts were cultured in vitro. The rabbits were used as the animal model of distraction osteogenesis. The proliferation of osteoblasts was analysed through MTT methods. The osteogenesis was observed by histochemical and histoimmunochemical methods.
RESULTSPRP stimulated the proliferation of osteoblasts and facilitated distraction osteogenesis.
CONCLUSIONSPRP could accelerate the osteogenesis during bone distraction. The application of PRP in clinical practice might shorten the period of distraction osteogenesis.
