The physiological effects of resveratrol and its potential application in high altitude medicine.
- Author:
Hui-li ZHU
;
Hong-jing NIE
;
Pei-bing LI
;
Bing-nan DENG
;
Rui-feng DUAN
;
Hong JIN
;
Zhao-li CHEN
- Publication Type:Journal Article
- MeSH:
Altitude;
Humans;
Hypoxia;
drug therapy;
Polycythemia;
drug therapy;
Stilbenes;
pharmacology
- From:
Chinese Journal of Applied Physiology
2015;31(6):498-503
- CountryChina
- Language:English
-
Abstract:
Resveratrol, as a natural polyphenolic compound, has a wide range of beneficial effects, which includes anti-tumor, cardiovascular protection, anti-oxidant and estrogen-like effects, and so on. Its various physiological properties are closely related to the therapeutic principle for prevention and treatment of high altitude hypoxia injury. Resveratrol may play an important role in relieving or curing high altitude diseases, especially high altitude polycythemia(HAPC). However, the literature about study and application of resveratrol in plateau medicine field is rarely reported up to now. In this review, we summarized the physiological effects of resveratrol, discussed the possible main principle of resveratrol for HAPC therapy, and looked forward to resveratrol's perspective or potential application in high altitude medicine.