Association of CKMM gene A/G polymorphism and athletic performance of uyghurnationality.
- Author:
En-peng HE
;
Yan-hong LI
;
Jian-dong QIAN
;
Hua-wei YAN
- Publication Type:Journal Article
- MeSH: Alleles; Asian Continental Ancestry Group; genetics; Athletes; Athletic Performance; China; Creatine Kinase, MM Form; genetics; Gene Frequency; Genotype; Humans; Physical Endurance; genetics; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length
- From: Chinese Journal of Applied Physiology 2016;32(1):82-86
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVEDiscusses the distributive characters of the Creatine Kinase MM (CKMM) gene A/G Polymorphism in XinjiangUyghur, One hundred and fourtheen athletes and 441 general population of Uyghur were involved in the study.
METHODSPolymerase chain reaction-restriction fragment length polymorphism was used.
RESULTS(1) The CKMM gene A/G frequency in Uyghur general population was(AA, AG and GG) 0.497, 0.392 and 0.111, the result test by Hardy-Weinberg (H-W) equilibrium and x² = 2.72, P = 0.1, df = 2, indicated that the control group had representative. (2) AA, AG and GG genotype frequency of power-oriented athlete respectively was 0.442,0.302 and 0.256, frequency of GG genotype and G allele was higher than the control group, there were significant differences compared to thecontrol( P < 0.05, df = 2); (3) A/G genotype frequency of Endurance-oriented athletere spectively was 0.571, 0.400 and 0.029, there were nosignificant differences compared to the controls ( P > 0. 05, df = 2). (4) A/G genotype frequency of Uyghur soccer athletes respectively was0.472, 0.361 and 0.167, G allele was higher than the Endurance-oriented athlete and lower than the power-oriented athletes. and no significant differences compared to the controls( P > 0.05, df = 2).
CONCLUSIONThe results indicate that the CKMM gene GG genotype and G alleleare represented in power-oriented athletes, but don't find A/G polymorphism correlation with endurance and the football sport performance.