Analysis of death-related factors of type B aortic dissection treated medically during the acute phase.
- Author:
Lei WANG
1
;
Shi-jie XIN
;
Liang XIAO
;
Ling REN
;
Jian ZHANG
;
Hai-di HU
;
Qing-bin SONG
;
Xin-hua HU
;
Ping ZHANG
;
Zan-song ZHANG
;
De-hua YANG
;
Chuan-jiang WANG
;
Zhi-quan DUAN
;
Ke XU
Author Information
- Publication Type:Journal Article
- MeSH: Acute Disease; Adult; Aged; Aneurysm, Dissecting; drug therapy; mortality; Aortic Aneurysm; drug therapy; mortality; Cause of Death; Female; Humans; Logistic Models; Male; Middle Aged; Retrospective Studies; Risk Factors
- From: Chinese Journal of Surgery 2010;48(5):335-337
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo analyze the death-related risk factors of type B aortic dissection treated medically during the acute phase (symptoms presenting within 14 d), and to determine the predictors of surgical indications for acute type B aortic dissection.
METHODSClinical data of 42 patients with acute type B aortic dissection admitted from January 2007 to May 2009 was retrospectively reviewed. There were 33 male and 9 female with a mean age of (50 +/- 12) years old. Therapy included analgesia, controlled hypotension and beta-receptor blocker, the mortality in acute phase was 33.3% (14/42). Univariate and multivariate logistic regression analyses were performed to identify the predictors of the death in acute phase.
RESULTSIn univariate logistic regression analysis, the malperfusion of aortic branches (P = 0.018) and maximum aortic diameter (P = 0.002) were significant predictors of death. In the multivariate logistic regression model, the malperfusion of aortic branches (P = 0.041) and maximum aortic diameter (P = 0.005) were also considered as the significant death-related factors.Risk of death augmented significantly (P = 0.000) when the maximum aortic diameter over 40 mm.
CONCLUSIONMalperfusion of aortic branches and the large maximum aortic diameter (> 40 mm) are the indications of surgery or endovascular therapy for acute type B aortic dissection.