A Case of Extensive Stage Small Cell Lung Cancer Presenting as an Acute Appendicitis with Perforation.
10.4046/trd.2008.65.3.230
- Author:
Dong Won SHIN
1
;
Moon Han CHOI
;
Seung Sik PARK
;
Sung Woo PARK
;
Ki Up KIM
;
An Soo JANG
;
Choon Sik PARK
;
Cheol Wan LIM
;
Eun Suk KO
;
Sang Hyun PAIK
;
Do Jin KIM
Author Information
1. Department of Internal Medicine, Bucheon Hospital, Soonchunhyang University School of Medicine, Bucheon, Korea. kdj@schbc.ac.kr
- Publication Type:Case Report
- Keywords:
Appendix;
Metastasis;
Small cell carcinoma
- MeSH:
Appendicitis;
Appendix;
Biopsy;
Bronchoscopy;
Carcinoma, Small Cell;
Cough;
Frozen Sections;
Humans;
Incidence;
Keratins;
Lung;
Neoplasm Metastasis;
Nuclear Proteins;
Positron-Emission Tomography;
Small Cell Lung Carcinoma;
Sputum;
Synaptophysin;
Thorax;
Thyroid Gland;
Transcription Factors
- From:Tuberculosis and Respiratory Diseases
2008;65(3):230-234
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The incidence of appendiceal metastatic cancer is quite low. In particular, in small cell lung cancer, there is a very low incidence of a metastasis to the appendix. A 75-years old man with right lower quadrant pain, cough and sputum was transferred to our hospital. Abdominal CT revealed acute appendicitis with a perforation. The patient underwent surgery. The frozen sections of the tissue obtained during surgery, indicated a malignancy, but a right hemicolectomy was not performed due to the patient's poor general condition. The histology findings of the appendix were identified as a small cell carcinoma. The abdominal CT scan and chest x-ray at admission day showed a mass in the right lower lobe, and a further evaluation of the lesion was performed including positron emission tomography and flexible bronchoscopy with a biopsy. The pathology findings of the lung mass were also small cell lung cancer. The specimens from both sites stained positive for cytokeratin, cluster designation 56, synaptophysin, chromogranin-A and thyroid transcription factor 1. It was concluded that the appendiceal small cell cancer originated from the lung.
