Dyscoagulation in the adult patients with chronic glomerulonephritis-related nephrotic syndrome
- Author:
kiem Hoang Ha
- Publication Type:Journal Article
- Keywords:
nephrotic syndrome
- MeSH:
Glomerulonephritis;
Nephrotic Syndrome;
Blood Coagulation
- From:Journal of Practical Medicine
2002;435(11):26-29
- CountryViet Nam
- Language:Vietnamese
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Abstract:
35 adult patients with nephrotic syndrome that related to chronic glomerulonephritis were studied. 15 healthy people matched to age served as control. The results showed the dyscoagulation on patients with nephrotic syndrome with followed features: Elevation of plasma fibrinogen levels. 25% of patients had plasma fibrinogen levels as high as 1000mg/dl. There was no patient with low plasma fibrinogen levels. Platelet count was elevated. There was no patient with low platelet count. Platelet aggregation was elevated. There was significant positive correlation between plasma fibrinogen and cholesterol levels (r = 0.38) and between plasma fibrinogen and 24-hour urinary protein levels (r=0.3). There was a negative correlation between the increase in platelet aggregation and the reduction in plasma albumin level (r=0.43)
