Clinical characteristics and laboratory assay of adult Japanese encephalitis patiens in an outbreak in Yuncheng, Shanxi province, 2006
10.3760/cma.j.issn.1003-9279.2008.02.005
- VernacularTitle:2006年山西省运城市成人流行性乙型脑炎临床特征与实验室检验
- Author:
Ding-Lin ZHANG
1
;
Lu-Bao MA
;
Shi-Hong FU
;
Li-Hua WANG
;
Huan-Yu WANG
;
Min ZHANG
;
Zhi-Gan WEI
;
Guo-Gang LI
;
Xiao-Feng CUI
;
Hong-Ge LEI
;
Xiao-Hong SUN
;
Xin-Jun LV
;
Ming-Hua LI
;
Guo-Dong LIANG
Author Information
1. 山西省运城市第二医院
- Keywords:
Encephalitis virus,Japanese;
IgM antibody;
Neutralization tests
- From:
Chinese Journal of Experimental and Clinical Virology
2008;22(2):95-97
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the clinical and laboratory characteristics of adult Japanese encephalitis (JE) patiens in a JE outbreak in Yuncheng, Shanxi province in 2006. Methods All the clinical data from the Second People's Hospital in Yuneheng city were analyzed, part of patients' sera and cerebrospinal fluid were tested by serology and RT-PCR. Results The majority of patients were middle-aged and elderly, 77.8 % (35/45)of the total cases were more than 40 years old. Severe and fulminating type eases accounted for 60.0% (27/45) . Most patients had underlying diseases. IgM antibody to JE virus (JEV) in serum was positive in each of the 45 patients analyzed and 4-fold or greater rise in sera neutralization antibody titer were found in convalescent serum. JEV nucleic acid was positive in part of cerebrospinal fluid specimens. Conclusion Viral encephalitis emerged in Yuncheng city, Shanxi province was Japanese encephalitis B, and most of the eases belonged to elderly group.
