The effect of HAART to serum soluble interleukin-2 receptors in AIDS patients.
- Author:
Gui-Zhen SUI
1
;
Hong-Hai ZHANG
;
Tong ZHANG
Author Information
- Publication Type:Journal Article
- MeSH: Acquired Immunodeficiency Syndrome; drug therapy; immunology; Adult; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Female; Humans; Male; Middle Aged; Receptors, Interleukin-2; blood; Viral Load; Young Adult
- From: Chinese Journal of Experimental and Clinical Virology 2008;22(3):219-221
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo approach the effect of HAART to serum soluble interleukin-2 receptors in AIDS patients.
METHODS90 cases of AIDS patients were chosen for detection of their slL-2R levels by enzyme-linked immunosorbent assay (ELISA), peripheral blood CD4 T cell counts by flow cytometry and viral load by Branch DNA amplification.
RESULTSThe slL-2R levels were (3154 +/- 905) m9icrog/ml before HAART and (2216 +/- 884) pg/ml after( P < 0.001), After HAART, the sIL-2R levels were(2846 +/- 963) microg/ml in ineffective HAART group and (1879 +/- 875) pg/ml in effective HAART group (P < 0.001).
CONCLUSIONThe serum sIL-2R levels of AIDS patients were lowered by effective HAART, and it could judge the efficacy of HAART in same extent.
