Genotypes of hepatitis B virus in Henan Luohe area.
- Author:
Fu-Qing WANG
1
;
Xiao-Lei HUANG
;
Ai-Qin LI
;
Jian-Guo WANG
;
Fu-Hua ZHANG
;
Yan-Bing CUI
;
Yao YI
;
Si-Yong CHEN
Author Information
- Publication Type:Journal Article
- MeSH: Adolescent; Adult; Aged; China; Female; Genotype; Hepatitis B; virology; Hepatitis B Surface Antigens; blood; genetics; Hepatitis B virus; classification; genetics; isolation & purification; Humans; Male; Middle Aged; Phylogeny; Young Adult
- From: Chinese Journal of Experimental and Clinical Virology 2008;22(4):257-259
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo determine the main genotype of hepatitis B virus (HBV) prevailed in Henan Luohe area.
METHODSSerum specimens were collected from 94 HBsAg positive individuals, and HBV S gene were obtained by PCR amplifying, and the gene sequences were analyzed and the polygenetic tree was drawn by the software MEGA3.
RESULTSAbout 75.7% samples of HBV S gene clustered in genotype C, about 20% samples clustered at genotype B in the HBV polygenetic tree, about 4.3% samples clustered at genotype D in the HBV polygenetic tree.
CONCLUSIONThe main genotype of hepatitis B virus prevalent in Henan Luohe is genotype C, genotype B is rarely seen, and genotype D is rarely seen.
