Genotypes of hepatitis B virus in Henan Luohe area
10.3760/cma.j.issn.1003-9279.2008.04.006
- VernacularTitle:河南省漯河地区乙型肝炎病毒基因型别的初步研究
- Author:
Fu-Qing WANG
1
;
Xiao-Lei HUANG
;
Ai-Qin LI
;
Jian-Guo WANG
;
Fu-Hua ZHANG
;
Yan-Bing CUI
;
Yao YI
;
SI-Yong CHEN
Author Information
1. 漯河医学高等专科学校
- Keywords:
Hepatitis B virus;
Genotype
- From:
Chinese Journal of Experimental and Clinical Virology
2008;22(4):257-259
- CountryChina
- Language:Chinese
-
Abstract:
Objective To determine the main genotype of hepatitis B virus(HBV) prevailed in Henan Luohe area. Methods Serum specimens were collected from 94 HBsAg positive individuals, and HBV S gene were obtained by PCR amplifying, and the gene sequences were analyzed and the polygenetic tree was drawn by the software MEGA3. Results About 75.7% samples of HBV S gene clustered in genotype C, about 20% samples clustered at genotype B in the HBV polygenetie tree, about 4.3% samples clustered at genotype D in the HBV pelygenetic tree. Conclusion The main genotype of hepatitis B virus prevalent in Henan Luohe is genotype C,genotype B is rarely seen, and genotype D is rarely seen.
