Detection of cryptosporidium infection among AIDS patients in Guangdong and Yunnan.
- Author:
Xiao-hua LE
1
;
Hui WANG
;
Ji-zhou GOU
;
Xin-chun CHEN
;
Gui-lin YANG
;
Qian-ting YANG
;
Xiao-he LI
;
Bo-ping ZHOU
;
Hui-qin LI
;
Wei-ping CAI
Author Information
- Publication Type:Journal Article
- MeSH: AIDS-Related Opportunistic Infections; parasitology; Acquired Immunodeficiency Syndrome; complications; parasitology; Animals; Antigens, Protozoan; CD4 Lymphocyte Count; China; Cryptosporidiosis; diagnosis; etiology; immunology; parasitology; Cryptosporidium; chemistry; isolation & purification; Feces; parasitology; Flow Cytometry; HIV Infections; parasitology; Humans; Oocysts; Staining and Labeling
- From: Chinese Journal of Experimental and Clinical Virology 2008;22(5):339-341
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the infection of Cryptosporidium and its epidemiological characteristics in AIDS patients of Southern China.
METHODSStool samples colleted from AIDS confirmed patients. The samples were detected for oocyst of Cryptosporidium by acid fast bacteria stain and indirect fluorescent antibody stain respectively, CD4 count was detected by Flow Cytometry.
RESULTS212 samples of fresh stool obtained from the AIDS patients who live in Guangdong and Yunnan province. The total infection rate of Cryptosporidium in AIDS patients was 4.25% (9/212), the infectious rate of oocyst in the group of 50- 59-years-old was significantly higher than those in 30-39 (P < 0.01); the infectious rate of oocyst in patients with antiretroviral therapy (ART) was also significantly lower (P = 0.0000); we found the patients coinfected with Cryptosporidium with CD4 count all below 100 cells/microl. However, there were no any difference between the infectious rate to the patient's gender, areas and stool shape.
CONCLUSIONAIDS patients infected by Cryptosporidium are not rare in southern China, and the infectious rate was lower than western country. Patients received ART could decrease the infectious rate of Cryptosporidium, Cryptosporidium always happen in patient whose CD4 count was very low (< 100 cells/microl).
