The Prognostic Factors of Pneumonia with Septic Shock in Patients Presenting to the Emergency Department.
10.4266/kjccm.2015.30.4.258
- Author:
Jong Won KIM
;
Jin Joo KIM
;
Hyuk Jun YANG
;
Yong Su LIM
;
Jin Seong CHO
;
In Cheol HWANG
;
Sang Hyun HAN
- Publication Type:Original Article
- Keywords:
mortality;
outcome;
pneumonia;
shock, septic
- MeSH:
Anoxia;
APACHE;
Cause of Death;
Communicable Diseases;
Emergencies*;
Emergency Service, Hospital*;
Humans;
Korea;
Leukopenia;
Mortality;
Pneumonia*;
Prognosis;
Retrospective Studies;
Shock, Septic*
- From:Korean Journal of Critical Care Medicine
2015;30(4):258-264
- CountryRepublic of Korea
- Language:English
-
Abstract:
BACKGROUND: Pneumonia is the most common cause of death among patients with infectious disease in Korea. However, studies of pneumonia with septic shock in patients presenting to the emergency department are limited. The aim of this study was to investigate the prognostic factors associated with pneumonia with septic shock in patients presenting to the emergency department. METHODS: From January 2008 to September 2014, patients with pneumonia with septic shock admitted through the emergency department were retrospectively examined. RESULTS: Of the 561,845 patients who visited the emergency department, 398 were admitted for pneumonia with septic shock. The 28-day mortality rate in these patients was 36.4%. The independent prognostic factors were old age (>70 yrs) (odds ratio [OR], 2.42; 95%, confidence interval [CI], 1.35-4.32), Acute Physiology and Chronic Health Evaluation (APACHE) II score (OR, 1.04; 95% CI, 1.01-1.08), leukopenia (OR, 3.63; 95% CI, 1.48-8.94), prolonged PT-INR (OR, 2.53; 95% CI, 1.41-4.54), and hypoxemia (OR, 2.88; 95% CI, 1.30-6.38). CONCLUSIONS: A poor prognosis of patients with pneumonia is associated with old age (>70 yrs), increased APACHE II score, leukopenia, prolonged PT-INR, and hypoxemia.