Effects of dentine phosphoprotein on remineralization of demineralized dentine.
- Author:
Song-jiang LUO
1
;
Yu-jing LI
;
Ling WAN
;
Ying SU
;
Li-hua GE
Author Information
- Publication Type:Journal Article
- MeSH: Adolescent; Child; Dentin; chemistry; Humans; In Vitro Techniques; Phosphoproteins; isolation & purification; physiology; Tooth Demineralization; Tooth Remineralization
- From:Chinese Journal of Stomatology 2003;38(2):96-99
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the relationship between dentine phosphoprotein (DPP) and remineralization of demineralized dentine.
METHODS(1) Soluble DPP was extracted with 1 mol/L NaCl from demineralized dentine and was evaluated. (2) Soluble DPP was removed with 0.1 mol/L NaCl or was not removed from demineralized dentine sections in human tooth roots. Then all sections were subjected to remineralization treatment, and remineralization degrees were compared by atomic absorption spectrum, SEM and microradiography.
RESULTS(1) Soluble DPP was extracted with 1 mol/L NaCl. (2) Removal of soluble DPP resulted in significantly lower calcium concentration in remineralization solution (P < 0.01), less mean light-absorbed value in demineralized dentin sections by microradiography (P < 0.01).
CONCLUSIONSSoluble DPP may have an inhibiting effect on remineralization of demineralized dentine, this study suggests that the remove of soluble DPP from root caries lesions may enhance their remineralization potential.
