Inhibition of remineralization by EDTA-soluble phosphate protein in dentin.
- Author:
Ling YU
1
;
Xue-jun GAO
;
Wan-chun CHEN
;
Dao-dan LIU
Author Information
- Publication Type:Journal Article
- MeSH: Dental Cementum; chemistry; metabolism; Dentin; chemistry; Edetic Acid; Humans; Phosphoproteins; analysis; physiology; Tooth Demineralization; metabolism; Tooth Remineralization
- From:Chinese Journal of Stomatology 2003;38(3):220-222
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the effect of removing EDTA-soluble phosphate protein in dentin on the later remineralization for the purpose of better understanding of mechanism of dentin phosphate proteins on dentin mineralization.
METHODSTo remove soluble phosphate protein by EDTA dissolution, then the remineralization rate was monitored by a constant composition crystal growth technique. The results were compared with those from the normal dentin and the dentin partially demineralized by acetic acid.
RESULTSFaster remineralization rates were found with dentin demineralized by EDTA (0.5 and 2 h) compared with normal dentin powder, while a slower rate was found with dentin demineralized by acetic acid. The increase of remineralization rate by removing phosphate protein from dentin was 100% more at 200 min after the start of the reaction.
CONCLUSIONEDTA-soluble phosphate protein in dentin has a great potential to inhibit remineralization.
