A study of calcitonin gene-related peptide-immunoreactive nerve fibers of rat molar pulp during traumatic occlusion and after removal.
- Author:
Zuo-qi HAO
1
;
Hong-chen LIU
;
Mei-ling ZHU
;
Li-jun DUAN
Author Information
- Publication Type:Journal Article
- MeSH: Animals; Calcitonin Gene-Related Peptide; analysis; Dental Occlusion, Traumatic; metabolism; pathology; therapy; Dental Pulp; innervation; Immunohistochemistry; Male; Molar; innervation; Nerve Fibers; chemistry; Rats; Rats, Sprague-Dawley
- From: Chinese Journal of Stomatology 2003;38(6):432-434
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the effect of traumatic occlusion on CGRP-immunoreactive (CGRP-IR) nerve fibres in rat molar pulp and observe the recovery of CGRP-IR nerve fibres after removal of traumatic occlusion.
METHODSTo observe immunohistochemically the change of CGRP-IR nerve fibres in molar pulp during traumatic occlusion and after removal.
RESULTSThe increase of number, density and morphology of CGRP-IR nerve fibres in traumatic occlusion group was more than in control group, however, the changes of CGRP-IR nerve fibres in removal of traumatic occlusion group were less than in control group.
CONCLUSIONSThe changes of CGRP-IR nerve fibres in number, morphology, and density are induced by traumatic occlusion in rat molar pulp, however, the nerve fibres recover to normal by removal of traumatic occlusion.