Thrombocytopenia and its related factors: a hospital-based, cross-sectional study.
- Author:
Shih Wei LAI
1
;
Ching Yi HUANG
;
Hsueh Chou LAI
;
Kuan Fu LIAO
;
Yen Miao LAI
;
Chiu Shong LIU
;
Tsann LIN
Author Information
- Publication Type:Journal Article
- MeSH: Academic Medical Centers; Adult; Age Factors; Aged; Aged, 80 and over; Cross-Sectional Studies; Female; Hepatitis C Antibodies; blood; Hepatitis C, Chronic; complications; epidemiology; Humans; Liver Cirrhosis; complications; epidemiology; Male; Middle Aged; Odds Ratio; Prevalence; Retrospective Studies; Splenomegaly; complications; epidemiology; Taiwan; epidemiology; Thrombocytopenia; complications; epidemiology; Young Adult
- From:Annals of the Academy of Medicine, Singapore 2010;39(1):9-12
- CountrySingapore
- Language:English
-
Abstract:
INTRODUCTIONThe objective of this study was to explore the association between thrombocytopenia and its related factors.
MATERIALS AND METHODSThis was a hospital-based, cross-sectional study. We retrospectively analysed the medical records of all patients who received periodic health examinations at a medical centre located at Taichung in Taiwan between 2000 and 2004. In all, 5585 subjects were included for further analysis. A complete physical examination, laboratory survey and abdominal ultrasonography were performed on each subject. The t-test, chi-square test and multivariate logistic regression analysis were used.
RESULTSThe subjects consisted of 3123 men (55.9%) and 2462 women (44.1%). The mean age was 49.4 +/- 12.3 years (range, 20 to 87). The overall prevalence of thrombocytopenia was found to be 0.5%, higher in men than in women (0.6% vs 0.4%, P = 0.504). After controlling for the other covariates, multivariate logistic regression analysis exhibited that the factors significantly related to thrombocytopenia were increasing age (OR, 1.04; 95% CI, 1.004-1.08), anti-HCV positive (OR, 5.24; 95% CI, 2.08-13.20), liver cirrhosis (OR, 7.93; 95% CI, 2.28-27.62), and splenomegaly (OR, 18.86; 95% CI, 6.86-51.87).
CONCLUSIONIt is advisable to further check the hepatic status, if thrombocytopenia is noted.
