Application of HPLC/ELSD fingerprint and constellation graphical clustering method applied to evaluate the quality of Qingkailing injection.
- Author:
Shi-Kai YAN
1
;
Wen-Feng XIN
;
Yi-Ming WANG
;
Guo-An LUO
;
Yi-Yu CHENG
Author Information
- Publication Type:Journal Article
- MeSH: Chromatography, High Pressure Liquid; methods; Cluster Analysis; Drug Combinations; Drugs, Chinese Herbal; administration & dosage; chemistry; isolation & purification; Injections; Light; Materia Medica; chemistry; Plants, Medicinal; chemistry; Quality Control; Scattering, Radiation
- From: Acta Pharmaceutica Sinica 2005;40(9):842-845
- CountryChina
- Language:Chinese
-
Abstract:
AIMTo evaluate the quality of Qingkailing injections effectively, and to develop a credible method for the quality control of traditional Chinese medicine.
METHODSFingerprints of 18 Qingkailing injection samples from various manufacturers were obtained by HPLC/ELSD, and quality evaluation was performed by constellation graphical clustering method.
RESULTSHPLC/ELSD and constellation graphical clustering method properly revealed the quality information apparently and accurately.
CONCLUSIONIt was an apparent, credible and efficient method for quality evaluation of Chinese medicines.
