Study of brainstem auditory evoked potentials and its correlation with pontine volume in olivopontocerebellar atrophy.
- Author:
Shan-Ying MAO
1
;
Jian-Zheng HUANG
;
Mei-Ping DING
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Case-Control Studies; Evoked Potentials, Auditory, Brain Stem; physiology; Female; Humans; Male; Middle Aged; Olivopontocerebellar Atrophies; pathology; physiopathology; Pons; pathology
- From: Chinese Journal of Applied Physiology 2007;23(3):324-327
- CountryChina
- Language:Chinese
-
Abstract:
AIMTo investigate the change of latency and interpeak latency of each component of BAEP (brainstem auditory evoked potential, BAEP) and its correlation with PV/PFV (pontine volume/posterior fossa volume, PV/PFV) ratio in OPCA (olivopontocerebellar atrophy, OPCA).
METHODSWe used Keypoint EMG/EP to determine waves I PL (peak latency, PL), III PL, V PL and I - III IPL (interpeak latency, IPL), III - V IPL, I - V IPL and used 1.5TMR 3D volume rendering software to determine PV (pontine volume, PV), CV(cerebellar volume, CV) and PFV (posterior fossa volume,PFV). Then calculated PV/PFV ratio, CV/PFV ratio and PV/ CV ratio in OPCA group and control group.
RESULTSCompared with control group, in OPCA group wave IIII PL, I - III IPL were significantly elongated (P < 0.05), III - V IPL was significantly shorten (P < 0.05), PV/PFV ratio was significantly decreased (P < 0.01); there was a positive correlation between III-V IPL and PV/PFV ratio (r = 0.83, P < 0.01).
CONCLUSIONIn patients with OPCA, III PL, I - III IPL of BAEP were elongated and III - V IPL of BAEP was shorten. III - V IPL became shorter when the volume of pontine decreased.
