Assessment of cardiac structure and function by echocardiographic values for male Balb/c mice.
- Author:
Ji-zheng MA
1
;
Xiao-xia TANG
;
Shu-shu ZHU
;
Heng-fang WU
;
Xiang-jian CHEN
;
Di XU
;
Di YANG
;
Ji-nan ZHANG
Author Information
- Publication Type:Journal Article
- MeSH: Animals; Echocardiography; Heart; physiology; Heart Ventricles; diagnostic imaging; Male; Mice; Mice, Inbred BALB C; Ventricular Function, Left
- From: Chinese Journal of Applied Physiology 2007;23(4):390-393
- CountryChina
- Language:Chinese
-
Abstract:
AIMTo assess the parameters of cardiac structure and function of male Balb/c mice by the echocardiography.
METHODSA total of 27 male Balb/c mice (from five to seven week old) were examined with a 13-MHz transthoracic linear-array transducer, hearts were removed from mice anesthetized with Nembutal, and the left ventricular (LV) mass were weighed.
RESULTSComplete 2-dimensional echocardiography for cardiac structure and function were obtained. Hemodynamic parameters were recorded. A correlation existed between LV weight (x) and echocardiographic LV mass (y) with the 2D) guided M-mode method: y = 1.15x + 3.26, (r = 0.80).
CONCLUSIONEchocardiography appears to be a promising approach for noninvasively assessing LV mass and function in mice.
