Characterization and influencing factors of visit-to-visit blood pressure variability of the population in a northern Chinese industrial city.

Huijun Cao; Shouling WU; Shuqiang LI; Haiyan Zhao; Chunyu Ruan; Yuntao WU; Aijun Xing; Kuibao LI; Jin Chen; Xinchun Yang; Jun Cai

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Characterization and influencing factors of visit-to-visit blood pressure variability of the population in a northern Chinese industrial city.

Author: Huijun CAO ¹ ; Shouling WU ² ; Shuqiang LI ³ ; Haiyan ZHAO ² ; Chunyu RUAN ² ; Yuntao WU ² ; Aijun XING ² ; Kuibao LI ¹ ; Jin CHEN ¹ ; Xinchun YANG ⁴ ; Jun CAI ¹
Author Information

1. Department of Cardiology, Chaoyang Hospital, Capital Medical University, Beijing 100020, China.
2. Department of Cardiology, Kailuan Hospital, Hebei United University, Tangshan, Hebei 063000, China.
3. Department of Cancer Immunology and AIDS, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA.
4. Department of Cardiology, Chaoyang Hospital, Capital Medical University, Beijing 100020, China. Email: yangxc2010@hotmail.com.
Publication Type:Journal Article
MeSH: Adult; Aged; Aged, 80 and over; Blood Pressure; physiology; C-Reactive Protein; metabolism; China; Cities; Female; Humans; Hypertension; physiopathology; Lipoproteins, HDL; blood; Lipoproteins, LDL; blood; Logistic Models; Male; Middle Aged; Triglycerides; blood; Waist Circumference; physiology
From: Chinese Medical Journal 2014;127(6):1022-1026
CountryChina
Language:English
Abstract:
BACKGROUNDBlood pressure variability (BPV) is a reliable prognostic factor for cardiovascular events. Currently there is a worldwide lack of large sample size studies in visit-to-visit BPV. Based on the Kailuan Study, we analyzed the visit-to-visit BPV of patients to investigate the range and influencing factors of BPV.
METHODSIn 11 hospitals in the Kailuan Company, 4 441 patients received routine health checkups. Physical examination measured blood pressure (BP), body height, body weight, and waist circumference, and body mass index was calculated. Blood samples were analyzed for plasma total cholesterol (TC), triglyceride (TG), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), fasting blood glucose (FBG), and high-sensitivity c-reactive protein (hs-CRP).
RESULTSThe effect of gender on systolic BPV was investigated. The average systolic BPV was 10.35 mmHg (1 mmHg = 0.133 kPa) overall, 10.54 mmHg in males and 10.06 mmHg in females. Multivariate Logistic regression analysis revealed that the age (RR = 1.022), systolic BP (SBP, RR = 1.007), LDL-C (RR = 1.098), and history of hypertension (RR = 1.273) were significant risk factors for higher systolic BPV. We found that aging (RR = 1.022), increased SBP (RR = 1.007), and a history of hypertension (RR = 1.394) were determinants of systolic BPV in males. The risk factors for systolic BPV of females were aging (RR = 1.017), increased SBP (RR = 1.009), increased LDL (RR = 1.136), and increased TG (RR = 1.157).
CONCLUSIONOur findings indicated that the systolic BPV is closely associated with age, SBP and history of hypertension.