Two Cases of the Angioimmunoblastic Lymphadenopathy Type of Peripheral T - cell Lymphoma : Different Clinical Courses According to Positivity to Epstein-Barr Virus.
10.5021/ad.1998.10.2.116
- Author:
Jae Wang KIM
;
Sang Ho NAM
;
Kwang Joong KIM
;
Chong Min KIM
;
Chong Ju LEE
- Publication Type:Case Report
- Keywords:
Peripheral T-cell lymphoma;
EBV
- MeSH:
Genome;
Herpesvirus 4, Human*;
Immunoblastic Lymphadenopathy*;
Lymphoma*;
Lymphoma, T-Cell, Peripheral;
Prognosis;
T-Lymphocytes
- From:Annals of Dermatology
1998;10(2):116-122
- CountryRepublic of Korea
- Language:English
-
Abstract:
Peripheral T-cel1 lymphoma(PTCL) encompasses histopathologically and clinically various spectra of cutaneous T-cell lymphoma(CTCL). In this report, we describe two cases of PTCL showing diRerent clinical courses according to EBV(Epstein-Barr virus) positivity. The chnical course of case 1 with EBV-associated PTCL was rapidby fatal and refractory to intensive chcmotherapy. However, in case 2, EBV genomes were not found in her lesional tissues and she showed an indolent clinical course withoaat systemic symptoms. Accordingly, serological and immunohistochemical investigations for EBV might be mandatory in cutaneous PTCL to evaluate clinical prognosis.
