Single nucleotide polymorphisms of slow troponin T gene in Han ethnic population from Northern China.
- Author:
Chun-Yan XU
1
;
Yang HU
;
Hai-Ping LIU
Author Information
- Publication Type:Journal Article
- MeSH: Adolescent; Adult; Ethnic Groups; genetics; Exons; Female; Gene Frequency; Genotype; Humans; Male; Polymorphism, Single Nucleotide; Troponin T; classification; genetics
- From: Chinese Journal of Applied Physiology 2006;22(4):430-433
- CountryChina
- Language:Chinese
-
Abstract:
AIMTo analyze the distribution of single nucleotide polymorphisms in Han ethnic population from Northern China.
METHODSAllele frequencies in a sample of healthy Chinese Hans (n = 204) were determined by polymerase chain reactions followed by restriction analyses with specific endonucleases.
RESULTSThe SNP 27916722 A/C in exon 11 from the NCBI database was not detected in this population. And there were significant differences between the allele frequencies of the SNPs (27930097 C/G and 27920978 C/T) in Han ethnic population from Northern China and those in the NCBI.
CONCLUSIONIt is suggested that the SNPs of sTnT are different in different ethnic populations.