The effect of swimming training on the expression of cardiovascular CGRPmRNA in rats.
- Author:
Yan-Rui LUO
1
;
Jie HE
;
Zheng-Tang QI
Author Information
- Publication Type:Journal Article
- MeSH: Animals; Calcitonin Gene-Related Peptide; genetics; metabolism; Cardiovascular System; metabolism; Male; Physical Conditioning, Animal; RNA, Messenger; genetics; Rats; Rats, Sprague-Dawley; Swimming; physiology
- From: Chinese Journal of Applied Physiology 2007;23(1):62-65
- CountryChina
- Language:Chinese
-
Abstract:
AIMRats cardiovascular expression of CGRPmRNA surveyed after an eight-week swimming training, and molecular mechanism of exercise-induced adaptation were studied.
METHODS24 purebred male SD rats were divided randomly into three groups (n = 8): control (CR), exhaust (ER), train (TR). After swimming training left ventricular muscle and main artery arch were extracted, we inspected the expression of CGRPmRNA by RT-PCR.
RESULTS(1) Comparing with the control group, once exhausting exercise had no significant effect on cardiovascular expression of CGRPmRNA. (2) Comparing with the control group, long-term aerobic swimming training upregulated significantly cardiac expression of CGRPmRNA.
CONCLUSIONLong-term aerobic training induced benign cardiac adaptation in molecular level. Long-term aerobic swimming training had no significant effect on vascular expression of CGRPmRNA.
