Determination of five boswellic acids in Boswellia serrata.
- Author:
Chun WANG
1
;
Lei XIA
;
Zhiqian SONG
;
Qing LI
;
Chao WANG
;
Linyan ZENG
;
Zhenli LIU
Author Information
- Publication Type:Journal Article
- MeSH: Boswellia; chemistry; Chromatography, High Pressure Liquid; Plant Extracts; analysis; isolation & purification; Triterpenes; analysis; isolation & purification
- From: China Journal of Chinese Materia Medica 2011;36(10):1330-1333
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo develop an HPLC method for determinating the contents of five boswellic acids in Boswellia serrata.
METHODAnalysis was performed on a zorbax SB C18 column eluted with acetonitrile-0.1% phosphoric acid in water as mobile phases in gradient elution and the detection wavelengths were 210 nm and 250 nm.
RESULTThe five ingredients were separated well. The content ranges of alpha-boswellic acid, beta-boswellic acid, 3-acetyl-beta-boswellic acid, 11-keto-beta-boswellic acid and 11-keto-beta-acetyl- boswellic acid were 8.68-16.1, 53.5-246.9, 38.4-192.9, 4.48-5.81, 32.7-44.2 mg x g(-1), respectively.
CONCLUSIONThe contents of five individual boswellic acids were different in 12 batches of B. serrata samples.