Rapid analysis of psoralen and isopsoralen in Psoralea corylifolia by microwave-assisted extraction.
- Author:
Yanfang LU
1
;
Jing AN
;
Ye JIANG
Author Information
- Publication Type:Journal Article
- MeSH: Chromatography, High Pressure Liquid; Ficusin; chemistry; Furocoumarins; chemistry; Microwaves; Psoralea; chemistry; Reproducibility of Results
- From: China Journal of Chinese Materia Medica 2011;36(9):1158-1161
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo establish a convenient and rapid method of microwave-assisted extraction (MAE) for the extraction of psoralen and isopsoralen in Psoralea corylifolia.
METHODThe effects of various parameters on the MAE were investigated with several single-factor tests, and compared with the traditional extraction.
RESULTThe optimal conditions of MAE were as follows: the extractine time was 3 min, and the ratio of solvent to material was 400 mL x g(-1) by using methanol as the solvent. Compared with soxhlet extraction, heat reflux extraction, and ultrasound-assisted extraction, MAE needed only 3 min to give the highest yield of psoralen and isopsoralen, while the other extraction methods needed several hours and gave lower yield.
CONCLUSIONThe proposed method has greatly shortened extraction time and improved extraction yield, so it provides a neotype, simple and rapid measure for the separation of psoralen and isopsoralen from P. corylifolia.
