Studies on chemical constituents in roots of Helicteres angustifolia.
- Author:
Yingrou WEI
1
;
Guocai WANG
;
Xiaoqi ZHANG
;
Ying WANG
;
Wencai YE
Author Information
- Publication Type:Journal Article
- MeSH: Magnetic Resonance Spectroscopy; Plant Roots; chemistry; Sitosterols; chemistry; Sterculiaceae; chemistry; Triterpenes; chemistry
- From: China Journal of Chinese Materia Medica 2011;36(9):1193-1197
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the chemical constituents of the roots of Helicteres angustifolia.
METHODThe compounds were isolated and purified by column chromatographic methods on silica gel, Sephadex LH-20, ODS and preparative HPLC. Their structures were elucidated on the basis of physicochemical properties and spectral data.
RESULTSFourteen compounds were isolated from this plant. Their structures were identified as methyl helicterate(1),3-acetoxybetulin(2),3beta-acetoxy-27-(p-hydroxyl)benzoyloxylup-20(29)-en-28-oic acid methyl ester(3),3beta-acetoxy-27-benzoyloxylup-20(29)-en-28-oic acid(4),3beta-acetoxybetulinic acid(5),pyracrenic acid(6),cucurbitacin D(7),cucurbitacin B(8),isocucurbitacin D(9),3beta-acetoxy-27-[(4-hydroxybenzoyl)oxy]olean-12-en-28-oic acid methyl ester (10),beta-sitosterol(11),2alpha,7beta,20alpha-trihydroxy-3beta,21-dimethoxy-5-pregnene(12), hexadecanoic acid(13), and daucosterol(14), respectively.
CONCLUSIONCompounds 5,8,9,13, 14 were isolated from this plant for the first time.
