Polypronuclear zygotes and clinical pregnancy after IVF.
- Author:
Hui-Rong YIN
1
;
Xiao-Qiao QIAN
;
Ling-Bo CAI
;
Ting FENG
;
Zheng-Jie YAN
;
Long MA
;
Jia-Yin LIU
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Age Factors; Female; Fertilization in Vitro; methods; Humans; Ovulation Induction; Pregnancy; Pregnancy Rate; Zygote
- From: National Journal of Andrology 2009;15(12):1072-1074
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the relationship between the percentage of polypronuclear zygotes and clinical pregnancy following IVF.
METHODSWe collected the data of 954 IVF cycles, and according the percentage of polypronuclear zygotes in the IVF cycles, allocated them to Groups A (without polypronuclear zygotes) , B (with < 30% polypronuclear zygotes) and C (with > or = 30% polypronuclear zygotes). Then we analyzed the relationship between the percentage of polypronuclear zygotes and the rate of clinical pregnancy.
RESULTSCompared with Group A, Group C showed a significantly lower rate of clinical pregnancy (43.2% vs 28. 1%, P < 0.05), while Group B exhibited a markedly higher rate (43.2% vs 52.36%, P < 0.05) and obviously decreased polypronuclear zygote formation with the increase of age (35.6% vs 24.1%, P < 0.05).
CONCLUSIONThe percentage of polypronuclear zygotes in IVF cycles may serve as a prognostic indicator of the clinical outcome.
