Low-dose tadalafil improves arterial erectile dysfunction.
- Author:
Zhi-Peng XU
1
;
Yun CHEN
;
Chao SUN
;
Yu-Tian DAI
Author Information
- Publication Type:Clinical Trial
- MeSH: Adult; Aged; Arteries; Carbolines; administration & dosage; therapeutic use; Erectile Dysfunction; drug therapy; etiology; Humans; Male; Middle Aged; Phosphodiesterase Inhibitors; administration & dosage; therapeutic use; Tadalafil
- From: National Journal of Andrology 2009;15(11):1014-1016
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo evaluate the effect of low-dose phosphodiesterase type 5 inhibitor tadalafil on arterial erectile dysfunction.
METHODSForty-three patients with arterial erectile dysfunction were requested to take 5 mg tadalafil after supper on alternate days for 4 weeks. All the patients were scored on IIEF-5 and received intracavernous injection of 10 microg prostaglandin E1, followed by measurement of the peak systolic velocity (PSV) of the cavernosal artery by color Doppler ultrasonography.
RESULTSStatistic analyses showed an obvious increase in the IIEF-5 score and PSV after the treatment, with significant differences from the baseline (P < 0.01).
CONCLUSIONLow-dose tadalafil can significantly improve the PSV of the cavernosal artery and hence the erectile function of arterial ED patients.
