Varicocele and male infertility.
- Author:
Yu-feng HUANG
1
Author Information
1. Department of Andrology, Nanjing General Hospital of Nanjing Military Region, Nanjing, Jiangsu 210002, China. huangyf@androl.cn
- Publication Type:Journal Article
- MeSH:
Humans;
Infertility, Male;
etiology;
surgery;
Male;
Varicocele;
complications;
surgery
- From:
National Journal of Andrology
2010;16(3):195-200
- CountryChina
- Language:Chinese
-
Abstract:
Varicocele is a most common and surgically correctable cause of male infertility, for which varicocelectomy is the major treatment. Recent years have witnessed a lot of efforts devoted to the pathomechanism of varicocele-induced male infertility and rapid progress in researches on its cellular and molecular mechanisms, mainly including apoptotic abnormality and oxidative stress of germ cells. Meanwhile, researchers are coming to a consensus on the indications of varicocelectomy as well as the advantages and disadvantage of different methods of the procedure. This review updates the cellular and molecular mechanisms of varicocele-induced male infertility and its clinical therapeutic strategies.
