Association of hepatitis C virus genotype with glycolipid iron metabolism in Gansu Han population.
- Author:
Xiaorong MAO
1
;
Xuebin PENG
;
Youcheng ZHANG
;
Linping LI
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Blood Glucose; metabolism; China; epidemiology; Female; Genotype; Hepacivirus; genetics; Hepatitis C; blood; epidemiology; Humans; Iron; blood; Lipids; blood; Male; Middle Aged
- From: Journal of Zhejiang University. Medical sciences 2013;42(3):345-349
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the association of hepatitis C virus (HCV) genotype with glycolipids iron metabolism in Gansu Han population.
METHODSThe genotypes of HCV 1b type and 2a type were detected in Gansu Han HCV carriers. The Glu, Insulin, CHOL, TG, UIBC, TRF, TIBC, SF, Serum Iron, AST, ALT, TBil, IBil, DBil, ALP, GGT were measured and compared between patients with different HCV genotypes.
RESULTSThere were 84 cases with HCV1b type and 136 cases with 2a type. There were significant differences in TG, ALT, TRF, TIBC between 1b type and 2a type genotype HCV carriers.
CONCLUSIONThe 2a type HCV carriers may be more inclined to develop hyperlipidemia and liver damage, and 1b type HCV carriers are likely to have iron metabolism defect.
