Localization and pathological examination of sentinel lymph node during operation in gastric cancer.
- Author:
Xi-bo FU
1
;
Xiang HU
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Aged; Female; Humans; Male; Methylene Blue; Middle Aged; Neoplasm Staging; Sentinel Lymph Node Biopsy; Stomach Neoplasms; diagnosis; pathology
- From: Chinese Journal of Gastrointestinal Surgery 2005;8(1):29-31
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo evaluate the application of sentinel lymph node (SLN) biopsy in diagnosis and treatment of gastric cancer.
METHODSThirty- eight patients with gastric cancer were divided into three groups (T(1); T(2); T(3)) according to tumor invasion depth. SLN was localized using methyl blue injection method. Metastatic lymph nodes were detected by immunohistochemical staining of cytokeratin (CK- 19).
RESULTSSLN(S ) were detected in all 38 patients and lymph node metastasis occurred in 18 cases. The sensitivity, false- negative rate, and diagnostic accuracy of SLN for lymph node metastasis were 83.3% 16.7% and 92.1% respectively. The diagnostic accuracy was 100% in T1 cases without false- negative cases, 94.1% in T(2) cases with one false- negative case, 75% in T(3) cases with two false- negative cases.
CONCLUSIONThe method of injecting methylene blue around the primary tumor is a feasible method that can determine SLN localization during operation.
