Studies on alkalodial constituents in leaves of Uncaria hirsuta.

Author: Wen-bo XIN ¹ ; Ping GU ; Gui-xin CHOU ; Zheng-tao WANG
Author Information

1. Key Laboratory of Standardization of Chinese Medicines, Institute of Chinese Materia Medica of Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Publication Type:Journal Article
MeSH: Alkaloids; chemistry; Drugs, Chinese Herbal; chemistry; Plant Leaves; chemistry; Uncaria; chemistry
From: China Journal of Chinese Materia Medica 2008;33(17):2124-2128
CountryChina
Language:Chinese
Abstract:
OBJECTIVETo study the alkaloidial constituents of the leaves of uncaria hirsuta.
METHODSome chromatographic methods were applied to isolate pure compounds and their structures were elucidated by spectroscopic methods.
RESULTEleven compounds were isolated and identified as 19-epi-3-iso-ajmalicine (1), 3-isoajmalicine (2), harman (3), mitraphylline (4), isomitraphylline (5), isorhynchophylline (6), corynoxine (7), rhynchophylline (8), isomitraphyllic acid (9), uncarine A (10) and uncarine B (11).
CONCLUSIONCompounds 1-9 were firstly isolated from this plant.