Fingerprint comparison of effective parts of Ermiao wan categorized formula in anti-gouty syndrome of damp and heat.
- Author:
Xin LI
1
;
Lian YIN
;
Jin-ao DUAN
;
An-wei DING
Author Information
- Publication Type:Journal Article
- MeSH: Alkaloids; chemistry; Chromatography, High Pressure Liquid; methods; Drugs, Chinese Herbal; chemistry; therapeutic use; Flavonoids; chemistry; Gout; drug therapy; Gout Suppressants; chemistry; therapeutic use; Hot Temperature
- From: China Journal of Chinese Materia Medica 2008;33(16):1971-1975
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the correlation in the material foundation in compatibility of Ermiao wan categorized formulas (Ermiaowan, Sanmiaowan, Simiaowan and modified Simiaowan) and to explore its characteristics changes.
METHODDetermined the fingerprint of the effective parts of Ermiao wan categorized formulas in anti-gouty syndrome of damp and heat and compared the composition features and compatibility changes of total peaks by establishing the HPLC fingerprint and using reference substances to identify the ingredients of the common peaks, the ascription and the source of the chromatographic peaks.
RESULTThe effective parts of modified Simiao Wan had 60 total peaks which come from the sites of alkaloids, flavonoids, organic acids. There were some change principles in the number of total peaks and relative peak area ratio between basic formula and categorized formulas.
CONCLUSIONErmiaowan categorized formulas have same substance-foundation and there are some correlations in the compatibility changes.
