Relationship between antioxidant activities and contents of active ingredients in Radix Scutellaria.
- Author:
Bin YANG
1
;
Ri-xin LIANG
;
Xiao-ning ZHOU
;
Wei GAO
;
Lu-qi HUANG
Author Information
- Publication Type:Journal Article
- MeSH: Animals; Antioxidants; chemistry; pharmacology; Drugs, Chinese Herbal; pharmacology; Lipid Peroxidation; drug effects; Microsomes, Liver; drug effects; metabolism; Rats; Rats, Wistar; Scutellaria; chemistry
- From: China Journal of Chinese Materia Medica 2008;33(16):2019-2022
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the relationship between the antioxidant activities and the contents of active ingredients in Radix Scutellaria.
METHODThe antioxidant activities of extracts and active ingredients of Radix Scutellaria in NADPH-dependent lipid peroxidation in rat liver microsome were assayed.
RESULTExtracts of Radix Scutellaria showed a 50% inhibition of lipid peroxidation in the concentration range of 2.72-18.27 mg x L(-1).
CONCLUSIONThe antioxidant activities of extracts of Radix Scutellaria are not only related with the contents but also the ratio of the active ingredients.
