Influences of jiejiu gankang granule on lipid metabolism and liver function of alcohol-fatty-liver about mice.
- Author:
Bin LI
1
;
Li WANG
;
Rong SUN
Author Information
- Publication Type:Journal Article
- MeSH: Animals; Disease Models, Animal; Drugs, Chinese Herbal; pharmacology; Fatty Liver, Alcoholic; metabolism; pathology; Lipid Metabolism; drug effects; Lipoproteins, LDL; blood; Liver; drug effects; metabolism; pathology; Malondialdehyde; blood; metabolism; Mice; Random Allocation; Superoxide Dismutase; metabolism; Triglycerides; blood; metabolism
- From: China Journal of Chinese Materia Medica 2008;33(16):2048-2050
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVEJiejiu Gankang granule had been observed the effect on the model of the alcohol-fatty-liver about mice on lipid metabolism.
METHODThere was the model of alcohol-fatty-liver adopted in this experiment. The effect had been observed of Jiejiu Gankang granule in different dosages on blood-lipoid metabolism, intrahepatic-lipoid metabolism, energy metabolism or and oxidative damage degree.
RESULTJiejiu Gankang granule can decrease the level of TG, LDL, MDA in blood obviously. It can decrease the content of Gn, MDA and improve the level of SOD in liver obviously.
CONCLUSIONThere was some reference of dosage dependence on the intensity of potency action in high, middle and low dosage of this drug.
