Current situation and consideration of pharmacokinetic study on multiple components of traditional Chinese medicine.
- Author:
Ling HAN
1
Author Information
1. Center for Drug Evaluation, State Food and Drug Administration, Beijing 100038, China. hanling92@sina.com
- Publication Type:Journal Article
- MeSH:
Drug Interactions;
Drugs, Chinese Herbal;
pharmacokinetics;
Medicine, Chinese Traditional;
methods
- From:
China Journal of Chinese Materia Medica
2008;33(21):2442-2448
- CountryChina
- Language:Chinese
-
Abstract:
Facing the current situation, the paper reviewed the specificity, difficulty and significance in studying the pharmacokinetics of the multiple components of traditional Chinese medicine. Some key points in present pharmacokinetic study were also analyzed respectively in this paper, including the pharmacokinetic patterns of the individual herb, the prescription and its active fraction traditional Chinese medicine, the mechanism underlying the integrative effect of traditional Chinese medicinal prescription, the interaction between traditional Chinese medicine and chemical drug, and also the different pharmacokinetic patterns in the pathological situations of "Zheng" in traditional Chinese medicine and disease in modern medicine and the differences caused by different drug preparations. In addition, some viewpoints and suggestions were also given together with the consideration of "The basic technical requirements for the injections of traditional Chinese medicine and natural medicine".
