Effects of dietary supplementation with clostridium butyricum on the growth performance and humoral immune response in Miichthys miiuy.
- Author:
Zeng-fu SONG
;
Tian-xing WU
;
Li-sheng CAI
;
Li-jing ZHANG
;
Xiao-dong ZHENG
- Publication Type:Letter
- MeSH:
Animal Feed;
microbiology;
Animals;
Antibody Formation;
physiology;
Clostridium butyricum;
immunology;
Dietary Supplements;
microbiology;
Fishes;
growth & development;
immunology;
Probiotics;
administration & dosage
- From:
Journal of Zhejiang University. Science. B
2006;7(7):596-602
- CountryChina
- Language:English
-
Abstract:
The effects of dietary supplementation with Clostridium butyricum on growth performance and humoral immune response in Miichthys miiuy were evaluated. One hundred and fifty Miichthys miiuy weighing approximately 200-260 g were divided into five groups and reared in 15 tanks with closed circuiting culture system. The animals were fed 5 diets: basal diet only (control) or supplemented of the basal diet with C. butyricum at doses of 10(3) (CB1), 10(5) (CB2), 10(7) (CB3) or 10(9) (CB4) CFU/g. Compared with the control, the serum phenoloxidase activity was significantly increased by the supplementation (P<0.05), acid phosphatases activity was increased significantly (P<0.05) at the doses of 10(9) CFU/g. Serum lysozyme activity peaked at dose of 10(7) CFU/g and in the skin mucus at dose of 10(9) CFU/g. Immunoglobulin M level in the serum and skin mucus was increased except at dose of 10(3) CFU/g (P<0.05). The growth at the dose of 10(9) CFU/g was higher than that of the control (P<0.05). It is concluded that supplementation of C. butyricum can mediate the humoral immune responses and improve the growth performance in Miichthys miiuy.
