Immunogenicity of formaldehyde and binary ethylenimine inactivated infectious bursal disease virus in broiler chicks.
- Author:
Mudasser HABIB
1
;
Iftikhar HUSSAIN
;
Hamid IRSHAD
;
Zong-zhao YANG
;
Jiang-bing SHUAI
;
Ning CHEN
Author Information
1. Department of Veterinary Microbiology, University of Agriculture, Faisalabad 38040, Pakistan. mudasserhabib@yahoo.com
- Publication Type:Journal Article
- MeSH:
Animals;
Antibodies, Viral;
blood;
Aziridines;
pharmacology;
Chickens;
Formaldehyde;
pharmacology;
Infectious bursal disease virus;
immunology;
Vaccination;
Vaccines, Inactivated;
immunology;
Viral Vaccines;
immunology
- From:
Journal of Zhejiang University. Science. B
2006;7(8):660-664
- CountryChina
- Language:English
-
Abstract:
Infectious bursal disease virus (IBDV) was inactivated by two different chemicals--formaldehyde and binary ethylenimine (BEI). Formaldehyde was used at 0.1% and 0.2%, while BEI was used at concentrations of 0.001 and 0.002 mol/L. These four vaccines were tested for their efficiency in generating humoral immune response in different groups of broiler chicks. Both BEI-inactivated vaccines gave relatively higher antibody titers and were almost twice as efficient as formaldehyde-inactivated ones.
