Metabonomics-a useful tool for individualized cancer therapy.
- Author:
Yanlan CHAI
1
;
Juan WANG
;
Zi LIU
Author Information
1. Department of Radiotherapy Oncology,The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, China.
- Publication Type:Journal Article
- MeSH:
Humans;
Metabolomics;
Neoplasms;
therapy
- From:
Journal of Zhejiang University. Medical sciences
2013;42(6):705-710
- CountryChina
- Language:Chinese
-
Abstract:
Metabonomics has developed rapidly in post-genome era, and becomes a hot topic of omics. The core idea of metabonomics is to determine the metabolites of relatively low-weight molecular in organisms or cells, by a series of analytical methods such as nuclear magnetic resonance, color spectrum and mass spectrogram, then to transform the data of metabolic pattern into useful information, by chemometric tools and pattern recognition software, and to reveal the essence of life activities of the body. With advantages of high-throughput, high-sensitivity and high-accuracy, metabolomics shows great potential and value in cancer individualized treatment. This paper introduces the concept,contents and methods of metabonomics and reviews its application in cancer individualized therapy.
