Bottleneck and development trend of bone xenograft for the treatment of bone defect.
- Author:
Bao-liang LI
;
Lei LIU
;
Wen-bo ZHAO
;
Fu-jun LUAN
;
Qin LI
- Publication Type:Journal Article
- MeSH:
Bone Transplantation;
methods;
Bone and Bones;
blood supply;
Humans;
Transplantation, Heterologous
- From:
China Journal of Orthopaedics and Traumatology
2015;28(12):1166-1170
- CountryChina
- Language:Chinese
-
Abstract:
Bone xenograft bone for the treatment of bone defect is one of the current research focus, which has advantages of extensive sources, low cost, simple preparation method. While the process of single bone xenograft bone in repairing bone defect is very long, and the clinical outcome is not satisfactory. The main problems focus on formation of bone and vascularization. Reconstituted bone xenograft combined with cells and xenogenic bone material could promote vascularization and bone fusion in vivo, thus achieve a clinical effect of autogenous bone in repairing bone defect.
