Furosteroidal saponin from Smilacina japonica.
- Author:
Shujie ZHAO
1
;
Limin YANG
;
Zhongming HAN
;
Mei HAN
Author Information
1. College of Chinese Medicinal Materials, Jilin Agricultural University, Changchun 130118, China. zhsjlong@163.com
- Publication Type:Journal Article
- MeSH:
Antineoplastic Agents, Phytogenic;
pharmacology;
Cell Line, Tumor;
Humans;
Magnetic Resonance Spectroscopy;
Maianthemum;
chemistry;
Saponins;
chemistry;
isolation & purification;
pharmacology
- From:
China Journal of Chinese Materia Medica
2011;36(24):3453-3456
- CountryChina
- Language:Chinese
-
Abstract:
Smilacina japonica is a perennial herb, belonging to Smilacina genus of Liliaceae. A new furosteroidal saponin (1) was isolated and purified from the ethanol extract of the rhizome of S. japonica by various column chromatography. Its structure was established as 26-O-beta-D-glucopyranosyl-(25R)-furost-5-en-3beta, 12, 17alpha, 22xi, 26-pentol-12-O-acetyle-3-O-alpha-L-rhamnopyranosyl-(1 --> 2)-beta-D-glucopyranoside by physical and chemical properties and IR, MS, 1D, 2D NMR techniques. It showed strong cytotoxicity against the SPC-A-1 cancer cell lines.
