Studies on the phenolic acid constituents from Chinese medicine "sheng-ma", rhizome of Cimicifuga foetida L.
- Author:
Xiao-hong ZHAO
1
;
Di-hua CHEN
;
Jian-yong SI
;
Rui-le PAN
;
Lian-gang SHEN
Author Information
- Publication Type:Journal Article
- MeSH: Caffeic Acids; chemistry; isolation & purification; Cimicifuga; chemistry; Coumaric Acids; chemistry; isolation & purification; Drugs, Chinese Herbal; chemistry; isolation & purification; Hydroxybenzoates; chemistry; isolation & purification; Molecular Conformation; Molecular Structure; Phenylacetates; chemistry; isolation & purification; Plants, Medicinal; chemistry; Rhizome; chemistry; Umbelliferones; chemistry; isolation & purification
- From: Acta Pharmaceutica Sinica 2002;37(7):535-538
- CountryChina
- Language:Chinese
-
Abstract:
AIMTo look for new active constituents from Chinese medicine "Sheng-ma", rhizome of Cimicifuga foetida L.
METHODSThe compounds were separated and purified by chromatography on silica gel and Sephadex LH-20. Their structures were determined by spectral analysis and chemical reaction.
RESULTSEight compounds were obtained and identified as cimicifugic acid (1), esculetin (2), caffeic acid methyl ester (3), 4-O-acetyl-caffeic acid (4), sinapic acid (5), caffeic acid (6), ferulic acid (7), isoferulic acid (8).
CONCLUSIONCompound 1 is a new compound, and compounds 2-7 were isolated from this plant for the first time.